Detail Information for IndEnz0018000452
IED ID IndEnz0018000452
Enzyme Type ID peroxidase000452
Protein Name Glutathione amide-dependent peroxidase
Prx/Grx
EC 1.11.1.17
Gene Name garA
Organism Marichromatium gracile (Chromatium gracile)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Chromatiales Chromatiaceae Marichromatium Marichromatium gracile (Chromatium gracile)
Enzyme Sequence MLQDRTGSRVPQVTFHTRSGHEWVDLTTDEIFAGKTVVVFSLPGAFTPTCSSSHVPRYNQLVPMFKEHGVDTVACVSVSVNDTFVMNEWQKTQHADDLLFIPDGNGEFTEGMGMLVEKDDLGFGKRSWRYSMLVRDGVVEKMFIEPEVEGDPYEVSDADTMLAHLAPNAPKPMDVSVFTRDGCPFCVMAKEALRNAGIDFEELVLNEDYTEQTLRAVANAVPQVEVNGELIGGSEAVEGWLKERASA
Enzyme Length 247
Uniprot Accession Number B3EWI1
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=2 glutathione amide + H2O2 = glutathione amide disulfide + 2 H2O; Xref=Rhea:RHEA:27437, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:59895, ChEBI:CHEBI:59896; EC=1.11.1.17; Evidence={ECO:0000269|PubMed:11399772};
DNA Binding
EC Number 1.11.1.17
Enzyme Function FUNCTION: Catalyzes the oxidation of glutathione amide (GASH) to produce glutathione amide disulfide (GASSAG). May play a role in GASH metabolism under anaerobic conditions as a sulfide carrier necessary for cytoplasmic sulfide oxidation. {ECO:0000269|PubMed:11399772}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Domain (2)
Keywords Direct protein sequencing;Oxidoreductase;Peroxidase
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 27,340
Kinetics
Metal Binding
Rhea ID RHEA:27437
Cross Reference Brenda