| IED ID | IndEnz0018000452 |
| Enzyme Type ID | peroxidase000452 |
| Protein Name |
Glutathione amide-dependent peroxidase Prx/Grx EC 1.11.1.17 |
| Gene Name | garA |
| Organism | Marichromatium gracile (Chromatium gracile) |
| Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Gammaproteobacteria Chromatiales Chromatiaceae Marichromatium Marichromatium gracile (Chromatium gracile) |
| Enzyme Sequence | MLQDRTGSRVPQVTFHTRSGHEWVDLTTDEIFAGKTVVVFSLPGAFTPTCSSSHVPRYNQLVPMFKEHGVDTVACVSVSVNDTFVMNEWQKTQHADDLLFIPDGNGEFTEGMGMLVEKDDLGFGKRSWRYSMLVRDGVVEKMFIEPEVEGDPYEVSDADTMLAHLAPNAPKPMDVSVFTRDGCPFCVMAKEALRNAGIDFEELVLNEDYTEQTLRAVANAVPQVEVNGELIGGSEAVEGWLKERASA |
| Enzyme Length | 247 |
| Uniprot Accession Number | B3EWI1 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 glutathione amide + H2O2 = glutathione amide disulfide + 2 H2O; Xref=Rhea:RHEA:27437, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:59895, ChEBI:CHEBI:59896; EC=1.11.1.17; Evidence={ECO:0000269|PubMed:11399772}; |
| DNA Binding | |
| EC Number | 1.11.1.17 |
| Enzyme Function | FUNCTION: Catalyzes the oxidation of glutathione amide (GASH) to produce glutathione amide disulfide (GASSAG). May play a role in GASH metabolism under anaerobic conditions as a sulfide carrier necessary for cytoplasmic sulfide oxidation. {ECO:0000269|PubMed:11399772}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (2) |
| Keywords | Direct protein sequencing;Oxidoreductase;Peroxidase |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 27,340 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:27437 |
| Cross Reference Brenda |