| IED ID | IndEnz0018000453 |
| Enzyme Type ID | peroxidase000453 |
| Protein Name |
Probable glutathione S-transferase gst-36 EC 2.5.1.18 GST class-sigma |
| Gene Name | gst-36 R07B1.4 |
| Organism | Caenorhabditis elegans |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
| Enzyme Sequence | MPHFKFYYFDVRGRGEAIRLLFHLADEKFDDERFGMEQWGVLKSEMPLGQVPVLEIDGVKISQTTAIARYLGHQFHRAGTNAVDCARLDMIAEVIQEFMSSSGMGKFSRVLLGMIQANKEQFFKENVLPDVEKYAPIVEKFLLENGNNGLLLGDRETWVDVFAAESFSKLIDYGSPDALDAYPHILALINRVFNHPNIKKYVSQRKATPA |
| Enzyme Length | 210 |
| Uniprot Accession Number | Q09607 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | BINDING 8; /note=Glutathione; /evidence=ECO:0000250|UniProtKB:O60760; BINDING 39; /note=Glutathione; /evidence=ECO:0000250|UniProtKB:O60760; BINDING 43; /note=Glutathione; /evidence=ECO:0000250|UniProtKB:P46088 |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18; |
| DNA Binding | |
| EC Number | 2.5.1.18 |
| Enzyme Function | FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Binding site (3); Chain (1); Domain (2); Region (2) |
| Keywords | Reference proteome;Transferase |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 14704431; 21177967; 22286215; 22560298; 23800452; 25487147; 25635455; 29348603; 31216475; 8183318; |
| Motif | |
| Gene Encoded By | |
| Mass | 23,876 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:16437 |
| Cross Reference Brenda |