| IED ID | IndEnz0018000470 |
| Enzyme Type ID | peroxidase000470 |
| Protein Name |
Glutathione s-transferase kappa 2 EC 2.5.1.18 |
| Gene Name | gstk-2 D2024.7 |
| Organism | Caenorhabditis elegans |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
| Enzyme Sequence | MPNRKVVKFFFDVISPYSYFGFEGITRHRSVWKTPIQMKPFFFAGVVRHTENPGLPLRIPIKEKYMHKDLLFSAQYWGIPFRLPKDYTNMMLNTSSIVPQRILVASQLRDNVLMEDVARGLWHRFYAYGKPIFTKSQVAEVLRDLHVKDVDELVMMSDSAEVKNILRENTDEAIGNGCFGAPWMHITDGHGKVLQTVFGSDRLPQVADFLAEPFKGPMREKKPNA |
| Enzyme Length | 225 |
| Uniprot Accession Number | Q18973 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | BINDING 52; /note=Glutathione; /evidence=ECO:0000250 |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18; |
| DNA Binding | |
| EC Number | 2.5.1.18 |
| Enzyme Function | FUNCTION: Has roles in respiratory and lipid metabolism. {ECO:0000269|PubMed:19663909}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Binding site (1); Chain (1); Region (2) |
| Keywords | Mitochondrion;Reference proteome;Transferase |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:19663909}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 17164286; 19343510; 21177967; 22286215; 22347378; 22560298; 23800452; 25487147; |
| Motif | |
| Gene Encoded By | |
| Mass | 25,951 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:16437 |
| Cross Reference Brenda |