| IED ID | IndEnz0018000504 |
| Enzyme Type ID | peroxidase000504 |
| Protein Name |
Putative steryl acetyl hydrolase mug81 EC 3.1.1.- Meiotically up-regulated gene 180 protein |
| Gene Name | mug180 SPBPB2B2.02 |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota Taphrinomycotina Schizosaccharomycetes Schizosaccharomycetales Schizosaccharomycetaceae Schizosaccharomyces Schizosaccharomyces pombe (Fission yeast) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Enzyme Sequence | MISLSLLYRILTLPIILVGTTILYFTIGTNFPHDELRHNLLSTLFCSSMLHLSKGLTVKDVRIFFHDSIGSTLLKNRKKLNSENELPNYGEKFTHKYDNQDMPDSVWLAKVNGMTKSDPIILHLHGGMMALPYDKVILVGLSNLYKLFSTTMNRPPSILLVDYSLVSQGYTYPKQVRECLNVYQVLISKGFRNITVLGESAGGTLILSFLYQISELSKLNKVVWPKGVALISPWLDLTNAKKIGSYRANDGLDVICYETLNRFGKAYVNNEESLFTSSVVNINMNCDISIWSKIPPIQDGKVLVLFGENEVFRDEILSWTSKIGLLKAYPNRVLMDKQGIHIGLFLEESPSIGPGMTNLDIWKKKFSVNSLYTFLRETFEE |
| Enzyme Length | 381 |
| Uniprot Accession Number | Q9HDV1 |
| Absorption | |
| Active Site | ACT_SITE 200; /evidence=ECO:0000250|UniProtKB:Q5NUF3 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.1.- |
| Enzyme Function | FUNCTION: Required for the deacetylation of acetylated sterols (By similarity). Has a role in meiosis. {ECO:0000250, ECO:0000269|PubMed:16303567}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Glycosylation (1); Motif (1); Topological domain (2); Transmembrane (1) |
| Keywords | Cytoplasm;Endoplasmic reticulum;Glycoprotein;Hydrolase;Meiosis;Membrane;Reference proteome;Signal-anchor;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Single-pass type II membrane protein {ECO:0000269|PubMed:16823372}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 20473289; 23697806; 27887640; 30726745; |
| Motif | MOTIF 125..127; /note=Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole; /evidence=ECO:0000250|UniProtKB:Q5NUF3 |
| Gene Encoded By | |
| Mass | 43,152 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |