Detail Information for IndEnz0018000545
IED ID IndEnz0018000545
Enzyme Type ID peroxidase000545
Protein Name Catalase-peroxidase
CP
EC 1.11.1.21
Peroxidase/catalase
Gene Name katG ECA1909
Organism Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Pectobacteriaceae Pectobacterium Pectobacterium atrosepticum (Erwinia carotovora subsp. atroseptica) Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)
Enzyme Sequence MDENKTKPTGKCPVMHGGNTSTGSSNTDWWPNALNLDILHQHDTKTNPLGSDFSYREALKTLDVDALKKDLHALMTDSQEWWPADWGHYGGLMIRMAWHSAGSYRTTDGRGGGGTGNQRFAPLNSWPDNVSLDKARRLLWPIKRKYGNKLSWADLIILAGTIAYESMGLKTFGFAFGREDIWQPEKDTYWGAEKEWLANSTERYGSDDRTSLENPLAAVQMGLIYVNPEGVDGKSDPLRTAQDMRVTFSRMAMNDEETVALTAGGHTVGKTHGNGDASLLGAAPESADVEEQGLGWHNPTGSGKGRYTVTSGLEGAWTTHPTQWDNGFFQMLLNHEWELRKSPAGASQWEPVSIKEEDKPVDVEDPSIRYNPMMTDADMALKVDPEYRKISERFSRDQAYFSEVFARAWFKLTHRDMGPKARYVGPDVPQEDLLWQDPVPAGRTDYDVDLVKARIAESSLSISELVATAWDSARTFRGSDMRGGANGARIRLAPQKDWVGNEPARLARVLVVLESIAAATGASVADTIVLAGNVGIEKAAKAAGVQVTVPFAPGRGDTTDALTDVESFDVLEPIHDGYRNWLKKDYAVSVEELMLDRTQLMGLTANEMTVLVGGLRVLGTNYGGTKHGVFTDREGALTNDFFVNLTDMKYTWKPYRKDLYEIRDRKTGEVKWTATRLDLVFGSNSILRAYAEVYAQDDSKEKFVNDFVAAWVKVMNADRFDLAE
Enzyme Length 724
Uniprot Accession Number Q6D5X9
Absorption
Active Site ACT_SITE 99; /note=Proton acceptor; /evidence=ECO:0000255|HAMAP-Rule:MF_01961
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=AH2 + H2O2 = A + 2 H2O; Xref=Rhea:RHEA:30275, ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:17499; EC=1.11.1.21; Evidence={ECO:0000255|HAMAP-Rule:MF_01961}; CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.21; Evidence={ECO:0000255|HAMAP-Rule:MF_01961};
DNA Binding
EC Number 1.11.1.21
Enzyme Function FUNCTION: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. {ECO:0000255|HAMAP-Rule:MF_01961}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Cross-link (2); Metal binding (1); Region (1); Site (1)
Keywords Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification PTM: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme. {ECO:0000255|HAMAP-Rule:MF_01961}.
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 80,456
Kinetics
Metal Binding METAL 266; /note=Iron (heme b axial ligand); /evidence=ECO:0000255|HAMAP-Rule:MF_01961
Rhea ID RHEA:30275; RHEA:20309
Cross Reference Brenda