| IED ID | IndEnz0018000816 |
| Enzyme Type ID | peroxidase000816 |
| Protein Name |
Probable microsomal glutathione S-transferase EC 2.5.1.18 |
| Gene Name | mgst DDB_G0290291 |
| Organism | Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold) |
| Enzyme Sequence | MPFDTKSIFPDFIVFPSAISTIAIGLWSVQAYKLGEARKRYNVKAPHVQGDPEFERIAHEYQNTSEALGAIIPATFMFSYYISPKCSLLLGGTWLVSKMLNCCSYCCKKEKENDCAKNVHTCLSHISFFALLGGSAFGIGSSLYNRYKL |
| Enzyme Length | 149 |
| Uniprot Accession Number | Q54GA9 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18; |
| DNA Binding | |
| EC Number | 2.5.1.18 |
| Enzyme Function | FUNCTION: May perform the conjugation of reduced glutathione to electrophiles. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Transmembrane (2) |
| Keywords | Membrane;Reference proteome;Transferase;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 15470253; |
| Motif | |
| Gene Encoded By | |
| Mass | 16,626 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:16437 |
| Cross Reference Brenda |