Detail Information for IndEnz0018000816
IED ID IndEnz0018000816
Enzyme Type ID peroxidase000816
Protein Name Probable microsomal glutathione S-transferase
EC 2.5.1.18
Gene Name mgst DDB_G0290291
Organism Dictyostelium discoideum (Slime mold)
Taxonomic Lineage cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold)
Enzyme Sequence MPFDTKSIFPDFIVFPSAISTIAIGLWSVQAYKLGEARKRYNVKAPHVQGDPEFERIAHEYQNTSEALGAIIPATFMFSYYISPKCSLLLGGTWLVSKMLNCCSYCCKKEKENDCAKNVHTCLSHISFFALLGGSAFGIGSSLYNRYKL
Enzyme Length 149
Uniprot Accession Number Q54GA9
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18;
DNA Binding
EC Number 2.5.1.18
Enzyme Function FUNCTION: May perform the conjugation of reduced glutathione to electrophiles. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Transmembrane (2)
Keywords Membrane;Reference proteome;Transferase;Transmembrane;Transmembrane helix
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 15470253;
Motif
Gene Encoded By
Mass 16,626
Kinetics
Metal Binding
Rhea ID RHEA:16437
Cross Reference Brenda