| IED ID | IndEnz0018000948 |
| Enzyme Type ID | peroxidase000948 |
| Protein Name |
Putative heme-binding peroxidase EC 1.11.1.- |
| Gene Name | CNE03890 |
| Organism | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Basidiomycota Agaricomycotina Tremellomycetes Tremellales (jelly fungi) Cryptococcaceae Cryptococcus Cryptococcus neoformans species complex Cryptococcus neoformans (Filobasidiella neoformans) Cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
| Enzyme Sequence | MASVKEGDYQALKEEIKKIMKQPGYDDGSAGPVLVRLAWHASGNFSLVEHNGGSNGAGMRFPPESVDPANAGLHYAISFLLPLQSANSWISHADLWTLAGVTAIEAMGGPQIPWEPGRLDYESEQAAVEHRGDVSNRLPDGALGAAHIRDVFGRMGFSDQEIVALSGAHNLGRCHADRSGFDGPWVVNPTRFSNQYFKLLLPGTRLMMLPTDMALIEDPSFRPWVEKYAADQNLFFKDFANAFGKLIELGVDRDDTGFARLAKKAAEEGKPLDKTAPPAGDETCPVSGAVGGGVQRAAGGGGCPFMAMQNREAKL |
| Enzyme Length | 315 |
| Uniprot Accession Number | P0CP56 |
| Absorption | |
| Active Site | ACT_SITE 40; /note="Proton acceptor"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00297, ECO:0000255|PROSITE-ProRule:PRU10012"; ACT_SITE 185; /note="Tryptophan radical intermediate"; /evidence="ECO:0000250" |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 1.11.1.- |
| Enzyme Function | FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Metal binding (1); Region (1); Site (1) |
| Keywords | Heme;Iron;Metal-binding;Oxidoreductase;Peroxidase;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 33,825 |
| Kinetics | |
| Metal Binding | METAL 169; /note=Iron (heme b axial ligand); /evidence=ECO:0000255|PROSITE-ProRule:PRU00297 |
| Rhea ID | |
| Cross Reference Brenda |