| IED ID | IndEnz0018000972 |
| Enzyme Type ID | peroxidase000972 |
| Protein Name |
Non-haem bromoperoxidase BPO-A2 EC 1.11.1.- BPO2 Bromide peroxidase |
| Gene Name | bpoA2 |
| Organism | Kitasatospora aureofaciens (Streptomyces aureofaciens) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Actinobacteria Actinomycetia (high G+C Gram-positive bacteria) Streptomycetales Streptomycetaceae Kitasatospora Kitasatospora aureofaciens (Streptomyces aureofaciens) |
| Enzyme Sequence | MPFITVGQENSTSIDLYYEDHGTGQPVVLIHGFPLSGHSWERQSAALLDAGYRVITYDRRGFGQSSQPTTGYDYDTFAADLNTVLETLDLQDAVLVGFSMGTGEVARYVSSYGTARIAKVAFLASLEPFLLKTDDNPDGAAPQEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRISEEAVRNSWNTAASGGFFAAAAAPTTWYTDFRADIPRIDVPALILHGTGDRTLPIENTARVFHKALPSAEYVEVEGAPHGLLWTHAEEVNTALLAFLAK |
| Enzyme Length | 278 |
| Uniprot Accession Number | P29715 |
| Absorption | |
| Active Site | ACT_SITE 99; /evidence=ECO:0000250|UniProtKB:P22862; ACT_SITE 229; /evidence=ECO:0000250|UniProtKB:P22862; ACT_SITE 258; /evidence=ECO:0000250|UniProtKB:P22862 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 1.11.1.- |
| Enzyme Function | FUNCTION: May be a chlorinating enzyme involved in 7-chlorotetracycline biosynthesis. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Beta strand (9); Chain (1); Domain (1); Helix (16); Initiator methionine (1); Turn (2) |
| Keywords | 3D-structure;Antibiotic biosynthesis;Direct protein sequencing;Oxidoreductase;Peroxidase;Plasmid |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | X-ray crystallography (10) |
| Cross Reference PDB | 1BRO; 1BRT; 3VDX; 4D9J; 4IQ4; 4ITV; 4IVJ; 4QES; 4QF0; 4QFF; |
| Mapped Pubmed ID | 22654051; 23621606; |
| Motif | |
| Gene Encoded By | Plasmid pOP2621 |
| Mass | 30,385 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda | 1.11.1.18; |