| IED ID | IndEnz0018000979 |
| Enzyme Type ID | peroxidase000979 |
| Protein Name |
Catalase-3 EC 1.11.1.6 |
| Gene Name | CAT3 At1g20620 F2D10.40 F5M15.5 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MDPYKYRPSSAYNAPFYTTNGGAPVSNNISSLTIGERGPVLLEDYHLIEKVANFTRERIPERVVHARGISAKGFFEVTHDISNLTCADFLRAPGVQTPVIVRFSTVVHERASPETMRDIRGFAVKFYTREGNFDLVGNNTPVFFIRDGIQFPDVVHALKPNPKTNIQEYWRILDYMSHLPESLLTWCWMFDDVGIPQDYRHMEGFGVHTYTLIAKSGKVLFVKFHWKPTCGIKNLTDEEAKVVGGANHSHATKDLHDAIASGNYPEWKLFIQTMDPADEDKFDFDPLDVTKIWPEDILPLQPVGRLVLNRTIDNFFNETEQLAFNPGLVVPGIYYSDDKLLQCRIFAYGDTQRHRLGPNYLQLPVNAPKCAHHNNHHEGFMNFMHRDEEINYYPSKFDPVRCAEKVPTPTNSYTGIRTKCVIKKENNFKQAGDRYRSWAPDRQDRFVKRWVEILSEPRLTHEIRGIWISYWSQADRSLGQKLASRLNVRPSI |
| Enzyme Length | 492 |
| Uniprot Accession Number | Q42547 |
| Absorption | |
| Active Site | ACT_SITE 65; /evidence=ECO:0000250; ACT_SITE 138; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; |
| DNA Binding | |
| EC Number | 1.11.1.6 |
| Enzyme Function | FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Erroneous gene model prediction (2); Metal binding (1); Sequence conflict (9) |
| Keywords | Alternative splicing;Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Peroxisome;Reference proteome |
| Interact With | C1KKL7 |
| Induction | INDUCTION: Induced by cadmium. {ECO:0000269|PubMed:16502469}. |
| Subcellular Location | SUBCELLULAR LOCATION: Peroxisome {ECO:0000269|PubMed:25700484}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 12154131; 12376630; 12736379; 12938931; 14581623; 14671022; 15028209; 15032878; 15539469; 15821981; 15971193; 16287169; 16336779; 17080932; 17317660; 17432890; 17587236; 17728292; 17785451; 18230142; 18431481; 18538804; 18633119; 18775970; 19017119; 19500300; 20018591; 20031914; 20138775; 20230493; 20405473; 20442276; 20736450; 20876333; 21622812; 21665322; 21665324; 22525681; 22771435; 23940555; 24018686; 24709150; 25966761; 26263174; 26379686; 26649488; 26969415; 27247031; 27472382; 27659495; 28627464; 28869112; 29223068; 29575603; 30291629; 30696119; 31121523; 31548265; 32093294; 32330424; 32344669; 32859078; 33199020; 33318632; 9617812; |
| Motif | |
| Gene Encoded By | |
| Mass | 56,695 |
| Kinetics | |
| Metal Binding | METAL 348; /note=Iron (heme axial ligand); /evidence=ECO:0000250 |
| Rhea ID | RHEA:20309 |
| Cross Reference Brenda |