| IED ID | IndEnz0018001019 |
| Enzyme Type ID | peroxidase001019 |
| Protein Name |
Cytoglobin Histoglobin HGb Stellate cell activation-associated protein |
| Gene Name | Cygb Stap |
| Organism | Rattus norvegicus (Rat) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Rattus Rattus norvegicus (Rat) |
| Enzyme Sequence | MEKVPGDMEIERRERNEELSEAERKAVQATWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVEPMYFKILSGVILDVIAEEFANDFPVETQKAWTKLRGLIYSHVTAAYKEVGWVQQVPNTTTLPATLPSSGP |
| Enzyme Length | 190 |
| Uniprot Accession Number | Q921A4 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Metal binding (2); Region (2) |
| Keywords | Cytoplasm;Direct protein sequencing;Heme;Iron;Metal-binding;Oxygen transport;Reference proteome;Transport |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 14647402; 14660570; 16581302; 20719976; |
| Motif | |
| Gene Encoded By | |
| Mass | 21,497 |
| Kinetics | |
| Metal Binding | METAL 81; /note=Iron (heme b distal ligand); /evidence=ECO:0000255|PROSITE-ProRule:PRU00238; METAL 113; /note=Iron (heme b proximal ligand); /evidence=ECO:0000255|PROSITE-ProRule:PRU00238 |
| Rhea ID | |
| Cross Reference Brenda |