IED ID | IndEnz0018001100 |
Enzyme Type ID | peroxidase001100 |
Protein Name |
Vegetative catalase EC 1.11.1.6 |
Gene Name | katA kat kat-19 BSU08820 |
Organism | Bacillus subtilis (strain 168) |
Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Bacillus Bacillus subtilis group Bacillus subtilis Bacillus subtilis subsp. subtilis Bacillus subtilis (strain 168) |
Enzyme Sequence | MSSNKLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGYFEVTNDVTKYTKAAFLSEVGKRTPLFIRFSTVAGELGSADTVRDPRGFAVKFYTEEGNYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPKTHLKNPTAVWDFWSLSPESLHQVTILMSDRGIPATLRHMHGFGSHTFKWTNAEGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYHTEDLFNAIENGDYPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLDRNPENYFAEVEQATFSPGTLVPGIDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRARNKVNNYQRDGQMRFDDNGGGSVYYEPNSFGGPKESPEDKQAAYPVQGIADSVSYDHYDHYTQAGDLYRLMSEDERTRLVENIVNAMKPVEKEEIKLRQIEHFYKADPEYGKRVAEGLGLPIKKDS |
Enzyme Length | 483 |
Uniprot Accession Number | P26901 |
Absorption | |
Active Site | ACT_SITE 54; /evidence="ECO:0000250|UniProtKB:P15202, ECO:0000255|PROSITE-ProRule:PRU10013"; ACT_SITE 127; /evidence="ECO:0000250|UniProtKB:P15202" |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000269|PubMed:8180695}; |
DNA Binding | |
EC Number | 1.11.1.6 |
Enzyme Function | FUNCTION: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. {ECO:0000305|PubMed:1756979, ECO:0000305|PubMed:8180695}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Chain (1); Initiator methionine (1); Metal binding (1); Region (2); Sequence conflict (2) |
Keywords | Cytoplasm;Direct protein sequencing;Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Reference proteome |
Interact With | |
Induction | INDUCTION: By hydrogen peroxide. {ECO:0000269|PubMed:8180695}. |
Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:21744456}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 54,791 |
Kinetics | |
Metal Binding | METAL 337; /note=Iron (heme axial ligand); /evidence=ECO:0000250|UniProtKB:P15202 |
Rhea ID | RHEA:20309 |
Cross Reference Brenda | 1.11.1.6; |