Detail Information for IndEnz0018001106
IED ID IndEnz0018001106
Enzyme Type ID peroxidase001106
Protein Name Catalase
EC 1.11.1.6
Gene Name katA
Organism Neisseria gonorrhoeae
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Betaproteobacteria Neisseriales Neisseriaceae Neisseria Neisseria gonorrhoeae
Enzyme Sequence MTTSKCPVTHLTMNNGAPVADNQNSLTAGTRGPLLTQDLWLNEKLADFVREVIPERRMHAKGSGAFGTFTVTRDITKYTRAKIFSEVGKKTEMFGRLATVAGERGADAYTRVRGFALKFYTEEGNWDVVGNNTPVFYPDLRKFPDLNKAVKRSAHQYSSATNNWDFWALLPEALHQVTIVMSDRGIPASYRHMHGFGSHTYSLWNEAGERFWVKFHFRSQQGIKNLTNEEAAKIIADDRESHQRDLYEAIERGEFPKWTMYIQVMPEADAAKVPYHPFDLTKVWPKKDYPLIEVAEFELNRNPENFFADVEQSAFAPSNLVPGIGASPDKMLQARLFNYADAQRYRLGVNFRQIPVNRPRCPVHSNQRDGQGRATELRQPAHYEPNSFGQWSQQPDFAEPPLKINGDAAHWDYRQDDDDYFSQPRALFNLMNDAQKQALFDNTAAAMGDAPDFIKYRHIRNCYRCDPAYGEGGSKALGLTVEEPQAARATDPALGQGGLL
Enzyme Length 500
Uniprot Accession Number Q59602
Absorption
Active Site ACT_SITE 59; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013; ACT_SITE 131; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10013};
DNA Binding
EC Number 1.11.1.6
Enzyme Function FUNCTION: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Metal binding (1)
Keywords Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 56,671
Kinetics
Metal Binding METAL 339; /note=Iron (heme axial ligand); /evidence=ECO:0000250
Rhea ID RHEA:20309
Cross Reference Brenda