IED ID | IndEnz0018001111 |
Enzyme Type ID | peroxidase001111 |
Protein Name |
Catalase EC 1.11.1.6 |
Gene Name | cta1 SPCC757.07c |
Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota Taphrinomycotina Schizosaccharomycetes Schizosaccharomycetales Schizosaccharomycetaceae Schizosaccharomyces Schizosaccharomyces pombe (Fission yeast) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Enzyme Sequence | MNSKDSNTVPVYTTNTGCPIFNPMAAARVGKGGPVLLQDSHLIDVFQHFDRERIPERVVHAKGSGAFGEFECTDDITKYTKHTMFSKVGKKTPMVARFSTVGGERGTPDTARDPRGFALKFYTDEGIFDMVGNNTPVFFLRDPAKFPLFIHTQKRNPQNDMKDATMFWDYLSQNAESIHQVMILFSDLGGTPYSYRFMDGFSSHTYKFVNDKGEFYYCKWHFITNQGTKGLTNEEAAALDGSNPDHARQDLFEAIERGDYPSWTLYVQVMTPQEAEKYRYNIFDLTKVWPHKDVPMQRVGRFTLNQNPTNFFADIEQAGFSPSHMVPGIEVSADPVLQVRTFSYPDTHRHRLGANFEQIPVNSPKCPVFNYSRDGPMNVNGNQGNWPNYPSSIRPLAKVQYEPDEGHEKWVGQVTYHMDEITDVDFEQPRAFWQNVLGKKPGQQDNFVKNVAGHLSGAISPVRERQYGVFTRVDSELGRRIREATEAEVKKMEEKAPKPINKGEPHMFQGSS |
Enzyme Length | 512 |
Uniprot Accession Number | P55306 |
Absorption | |
Active Site | ACT_SITE 60; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013; ACT_SITE 133; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10013}; |
DNA Binding | |
EC Number | 1.11.1.6 |
Enzyme Function | FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Chain (1); Erroneous initiation (1); Metal binding (1); Modified residue (1); Region (1) |
Keywords | Direct protein sequencing;Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Phosphoprotein;Reference proteome |
Interact With | |
Induction | |
Subcellular Location | |
Modified Residue | MOD_RES 363; /note=Phosphoserine; /evidence=ECO:0000269|PubMed:18257517 |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | 10380645; 10455235; 19547744; 20473289; 22212525; 23697806; 24521463; 24696293; 24763107; 25122751; 25720772; 26412298; 26567340; 27005325; 27298342; 29996109; 30726745; 33225241; 33823663; |
Motif | |
Gene Encoded By | |
Mass | 58,279 |
Kinetics | |
Metal Binding | METAL 344; /note=Iron (heme axial ligand); /evidence=ECO:0000250 |
Rhea ID | RHEA:20309 |
Cross Reference Brenda |