Detail Information for IndEnz0018001115
IED ID IndEnz0018001115
Enzyme Type ID peroxidase001115
Protein Name Catalase
EC 1.11.1.6
Gene Name katA SH1573
Organism Staphylococcus haemolyticus (strain JCSC1435)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Staphylococcaceae Staphylococcus Staphylococcus haemolyticus Staphylococcus haemolyticus (strain JCSC1435)
Enzyme Sequence MAKDDKRLTGLFGHPVSDRENSMTAGPRGPLLMQDAYFLEQMSHFDREVIPERRMHAKGSGAFGTFTVTNDITKYTNAKIFSEVGKQTEMFARFSTVAGERGAADLERDIRGFALKFYTEDGNWDLVGNNTPVFFFRDSKLFVSLNRAVKRDPRTNMRSPQNNWDFWTGVPEALHQVTILMSDRGMPKDFRHMHGFGSHTYSMYNDEGERVWVKYHFRTQQGIENYTDDEAAEIVGQDRESSQRDLYDAIENGDYPKWKMYIQVMTEEQAKNHPDNPFDLTKVWYKGDYPLIEVGEFELNRNPENYFMDVEQAAFAPTNIIPGLDFSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQPKGVGIENMCPFSRDGQMRFLDGNQGGGPHYYPNNKGVYQSQPEYKKPAFPVDGDGYEYNQRQDDDNYFEQPGKLFRLQSDDAKERIFTNTANAMDGVSEDVKHRHIRHCYKADPEYGKGVAKALEIDINDVDLEGTNDETYENF
Enzyme Length 503
Uniprot Accession Number Q4L643
Absorption
Active Site ACT_SITE 56; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013; ACT_SITE 129; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10013};
DNA Binding
EC Number 1.11.1.6
Enzyme Function FUNCTION: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Metal binding (1); Region (1)
Keywords Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 58,053
Kinetics
Metal Binding METAL 339; /note=Iron (heme axial ligand); /evidence=ECO:0000250
Rhea ID RHEA:20309
Cross Reference Brenda