Detail Information for IndEnz0018001145
IED ID IndEnz0018001145
Enzyme Type ID peroxidase001145
Protein Name Glutathione peroxidase 3
EC 1.11.1.9
Gene Name gpx-3 C11E4.2
Organism Caenorhabditis elegans
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans
Enzyme Sequence MAPGSVLSLAVALATIIGISCTATVDETMRWKECLNTNQSIFDFQIETLQGEYTDLSQYRGKVILLVNVATFCAYTQQYTDFNPMLEKYQAQGLTLVAFPCNQFYLQEPAENHELMNGLTYVRPGNGWTPHQELHIYGKIDVNGDNHHPLYEFVKESCPQTVDKIGKTDELMYNPVRPSDITWNFEKFLIDRNGQPRFRFHPTAWSHGDVVTPFIEQLLAEPAN
Enzyme Length 224
Uniprot Accession Number Q95003
Absorption
Active Site ACT_SITE 73; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=2 glutathione + H2O2 = glutathione disulfide + 2 H2O; Xref=Rhea:RHEA:16833, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:57925, ChEBI:CHEBI:58297; EC=1.11.1.9;
DNA Binding
EC Number 1.11.1.9
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Glycosylation (1); Signal peptide (1)
Keywords Glycoprotein;Oxidoreductase;Peroxidase;Reference proteome;Secreted;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..18; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 20439776; 22286215; 22560298; 23593298; 23800452; 25487147;
Motif
Gene Encoded By
Mass 25,556
Kinetics
Metal Binding
Rhea ID RHEA:16833
Cross Reference Brenda