Detail Information for IndEnz0018001152
IED ID IndEnz0018001152
Enzyme Type ID peroxidase001152
Protein Name Probable glutathione peroxidase 4
EC 1.11.1.9
Gene Name GPX4 At2g48150 F11L15.5
Organism Arabidopsis thaliana (Mouse-ear cress)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress)
Enzyme Sequence MGASASVPERSVHQFTVKDSSGKDLNMSIYQGKVLLIVNVASKCGFTETNYTQLTELYRKYKDQDFEILAFPCNQFLYQEPGTSQEAHEFACERFKAEYPVFQKVRVNGQNAAPIYKFLKASKPTFLGSRIKWNFTKFLVGKDGLVIDRYGTMVTPLSIEKDIKKALEDA
Enzyme Length 170
Uniprot Accession Number Q8L910
Absorption
Active Site ACT_SITE 44; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=2 glutathione + H2O2 = glutathione disulfide + 2 H2O; Xref=Rhea:RHEA:16833, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:57925, ChEBI:CHEBI:58297; EC=1.11.1.9;
DNA Binding
EC Number 1.11.1.9
Enzyme Function FUNCTION: May constitute a glutathione peroxidase-like protective system against oxidative stresses. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1)
Keywords Oxidoreductase;Peroxidase;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 12912986; 15890615; 16297073; 18493039; 18775970; 20736450; 24470466; 28102911; 31887216;
Motif
Gene Encoded By
Mass 19,300
Kinetics
Metal Binding
Rhea ID RHEA:16833
Cross Reference Brenda