Detail Information for IndEnz0018001155
IED ID IndEnz0018001155
Enzyme Type ID peroxidase001155
Protein Name Probable phospholipid hydroperoxide glutathione peroxidase
PHGPx
EC 1.11.1.12
Salt-associated protein
Gene Name CSA
Organism Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Sapindales Rutaceae Aurantioideae Citrus Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis)
Enzyme Sequence MASQSKTSVHDFTVKDAKGQDVDLSIYKGKLLLIVNVASQCGLTNSNYTELSQLYDKYKNQGLEILAFPCNQFGAQEPGDNEQIQEFACTRFKAEFPIFDKVDVNGDNAAPLYKHLKSSKGGLFGDSIKWNFSKFLVDKEGNVVERYAPTTSPLSIEKDIKKLLETA
Enzyme Length 167
Uniprot Accession Number Q06652
Absorption
Active Site ACT_SITE 41; /evidence=ECO:0000250|UniProtKB:P36968
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=a hydroperoxy polyunsaturated fatty acid + 2 glutathione = a hydroxy polyunsaturated fatty acid + glutathione disulfide + H2O; Xref=Rhea:RHEA:19057, ChEBI:CHEBI:15377, ChEBI:CHEBI:57925, ChEBI:CHEBI:58297, ChEBI:CHEBI:131871, ChEBI:CHEBI:134019; EC=1.11.1.12; Evidence={ECO:0000250|UniProtKB:P36968};
DNA Binding
EC Number 1.11.1.12
Enzyme Function FUNCTION: Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. {ECO:0000250|UniProtKB:O70325}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1)
Keywords Cytoplasm;Direct protein sequencing;Oxidoreductase;Peroxidase;Stress response
Interact With
Induction INDUCTION: By salt stress.
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 18,596
Kinetics
Metal Binding
Rhea ID RHEA:19057
Cross Reference Brenda