| IED ID | IndEnz0018001198 |
| Enzyme Type ID | peroxidase001198 |
| Protein Name |
Glutathione peroxidase EC 1.11.1.9 Di29 |
| Gene Name | |
| Organism | Dirofilaria immitis (Canine heartworm) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Spirurina Spiruromorpha Filarioidea Onchocercidae Dirofilaria Dirofilaria immitis (Canine heartworm) |
| Enzyme Sequence | MFIQLLILSYAILLQLIATQVADKQLPNLTKQCEPTSQTIYDFHVPTLDGSEKSLAEYRGKVLLLVNVATYCAYTFQYNDFNPMLENNSNGTLKILAFPCNQFLLQEPAENHELLNGLKYVRPGNGWEPHGNMHIFGKVEVNGDDHHPLYKFLKEHCPQTVPIIGDRHQLMYNPIGTNDIIWNFEKFLIDKKGHPRYRFHPSAWVQGSVIAPFIDELEREI |
| Enzyme Length | 221 |
| Uniprot Accession Number | P52033 |
| Absorption | |
| Active Site | ACT_SITE 72; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 glutathione + H2O2 = glutathione disulfide + 2 H2O; Xref=Rhea:RHEA:16833, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:57925, ChEBI:CHEBI:58297; EC=1.11.1.9; |
| DNA Binding | |
| EC Number | 1.11.1.9 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Glycosylation (3); Signal peptide (1) |
| Keywords | Glycoprotein;Oxidoreductase;Peroxidase;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 25,453 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:16833 |
| Cross Reference Brenda |