| IED ID | IndEnz0018001211 |
| Enzyme Type ID | peroxidase001211 |
| Protein Name |
Cytochrome c551 peroxidase Cytochrome c peroxidase EC 1.11.1.5 |
| Gene Name | ccp NE1315 |
| Organism | Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) |
| Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Betaproteobacteria Nitrosomonadales Nitrosomonadaceae Nitrosomonas Nitrosomonas europaea Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) |
| Enzyme Sequence | MIKRTLTVSLLSLSLGAMFASAGVMAANEPIQPIKAVTPENADMAELGKMLFFDPRLSKSGFISCNSCHNLSMGGTDNITTSIGHKWQQGPINAPTVLNSSMNLAQFWDGRAKDLKEQAAGPIANPKEMASTHEIAEKVVASMPQYRERFKKVFGSDEVTIDRITTAIAQFEETLVTPGSKFDKWLEGDKNALNQDELEGYNLFKGSGCVQCHNGPAVGGSSYQKMGVFKPYETKNPAAGRMDVTGNEADRNVFKVPTLRNIELTYPYFHDGGAATLEQAVETMGRIQLNREFNKDEVSKIVAFLKTLTGDQPDFKLPILPPSNNDTPRSQPYE |
| Enzyme Length | 334 |
| Uniprot Accession Number | P55929 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | BINDING 65; /note=Heme c 1; covalent; /evidence=ECO:0000255|PROSITE-ProRule:PRU00433; BINDING 68; /note=Heme c 1; covalent; /evidence=ECO:0000255|PROSITE-ProRule:PRU00433; BINDING 209; /note=Heme c 2; covalent; /evidence=ECO:0000255|PROSITE-ProRule:PRU00433; BINDING 212; /note=Heme c 2; covalent; /evidence=ECO:0000255|PROSITE-ProRule:PRU00433 |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 Fe(II)-[cytochrome c] + 2 H(+) + H2O2 = 2 Fe(III)-[cytochrome c] + 2 H2O; Xref=Rhea:RHEA:16581, Rhea:RHEA-COMP:10350, Rhea:RHEA-COMP:14399, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16240, ChEBI:CHEBI:29033, ChEBI:CHEBI:29034; EC=1.11.1.5; |
| DNA Binding | |
| EC Number | 1.11.1.5 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Beta strand (8); Binding site (4); Chain (1); Helix (17); Metal binding (4); Region (1); Sequence conflict (1); Signal peptide (1); Turn (3) |
| Keywords | 3D-structure;Direct protein sequencing;Electron transport;Heme;Iron;Metal-binding;Oxidoreductase;Periplasm;Peroxidase;Reference proteome;Repeat;Signal;Transport |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Periplasm {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | PTM: Binds 2 heme c groups covalently per subunit. |
| Signal Peptide | SIGNAL 1..26; /evidence=ECO:0000269|PubMed:8163487 |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 1IQC; |
| Mapped Pubmed ID | 11695895; |
| Motif | |
| Gene Encoded By | |
| Mass | 36,633 |
| Kinetics | |
| Metal Binding | METAL 69; /note=Iron (heme c 1 axial ligand); /evidence=ECO:0000255|PROSITE-ProRule:PRU00433; METAL 213; /note=Iron (heme c 2 axial ligand); /evidence=ECO:0000255|PROSITE-ProRule:PRU00433; METAL 270; /note=Iron (heme c 1 axial ligand); /evidence=ECO:0000255|PROSITE-ProRule:PRU00433; METAL 284; /note=Iron (heme c 2 axial ligand); /evidence=ECO:0000255|PROSITE-ProRule:PRU00433 |
| Rhea ID | RHEA:16581 |
| Cross Reference Brenda | 1.11.1.5; |