Detail Information for IndEnz0018001213
IED ID IndEnz0018001213
Enzyme Type ID peroxidase001213
Protein Name Dye-decolorizing peroxidase
DypB
EC 1.11.1.-
Gene Name RER_59910
Organism Rhodococcus erythropolis (strain PR4 / NBRC 100887)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Actinobacteria Actinomycetia (high G+C Gram-positive bacteria) Corynebacteriales Nocardiaceae Rhodococcus Rhodococcus erythropolis group Rhodococcus erythropolis (Arthrobacter picolinophilus) Rhodococcus erythropolis (strain PR4 / NBRC 100887)
Enzyme Sequence MALPAIPQPLLTPLTEAAIFLVFTIDEGGEQAVHDVLADISGLQRSIGFRVPAGGLAAVVGIGSDAWDRLFEGPRPAELHPFVELTGDKHHAPRTPGDLLFHIRARQMDLCFEFATVVTNRLAGAASVIDEVHGFKYFEQRDLMGFVDGTENPSGQAAYVAVTVGDEDPDFAGSSYVIVQKYLHDMSEWNSLPVEEQENVIGRSKLEDLEMDDDTKPANSHTALTVIEDESGEQIQILRDNMPFGHVGSAEMGTYFIGYSASPTVTEQMLTNMFIGNPVGNYDRILDFSTAVTGINFFVPTADFLDDPPDAPTRLVPEATFTAPISDGSLGIGSLKRSAQQ
Enzyme Length 341
Uniprot Accession Number C0ZVK5
Absorption
Active Site ACT_SITE 148; /note=Proton acceptor; /evidence=ECO:0000250|UniProtKB:Q47KB1
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 1.11.1.-
Enzyme Function FUNCTION: Cargo protein of a type 1 encapsulin nanocompartment (PubMed:24981030). Has both general peroxidase activity and dye-decolorizing activity. Can catalyze the oxidation of both protoporphyrinogen IX and coproporphyrinogen III to their corresponding porphyrins. Also efficiently decolorizes the dyes alizarin red and Cibacron blue F3GA (By similarity). This cargo-loaded encapsulin nanocompartment is probably involved in protection against oxidative damage (By similarity). {ECO:0000250|UniProtKB:I6WZG6, ECO:0000250|UniProtKB:P76536, ECO:0000269|PubMed:24981030}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Metal binding (1); Region (1)
Keywords Encapsulin nanocompartment;Heme;Iron;Metal-binding;Oxidoreductase;Peroxidase
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Encapsulin nanocompartment {ECO:0000269|PubMed:24981030}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 36,959
Kinetics
Metal Binding METAL 221; /note=Iron (heme proximal ligand); via tele nitrogen; /evidence=ECO:0000250|UniProtKB:Q8XBI9
Rhea ID
Cross Reference Brenda