IED ID | IndEnz0018001250 |
Enzyme Type ID | peroxidase001250 |
Protein Name |
Putative peroxisomal peroxiredoxin EC 1.11.1.- |
Gene Name | |
Organism | Lipomyces kononenkoae (Yeast) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Lipomycetaceae Lipomyces Lipomyces kononenkoae (Yeast) |
Enzyme Sequence | MTDKFPEDVKFLYIAYTPAKADITACGIPIPLDFDKEFRDKTVVIVAIPGAFTPTCTANHIPPFVEKFTALKSAGVDAVIVLSANDPFVQSAFGKALGVTDEAFIFASDPGAEFSKSAGLSLDLPPAFGTRTARYAIIVSNGVVKYVEKDSEGVAGSGVDAVLAAL |
Enzyme Length | 166 |
Uniprot Accession Number | Q01116 |
Absorption | |
Active Site | ACT_SITE 56; /note=Cysteine sulfenic acid (-SOH) intermediate; /evidence=ECO:0000250|UniProtKB:P38013 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=[protein]-dithiol + a hydroperoxide = [protein]-disulfide + an alcohol + H2O; Xref=Rhea:RHEA:10008, Rhea:RHEA-COMP:10593, Rhea:RHEA-COMP:10594, ChEBI:CHEBI:15377, ChEBI:CHEBI:29950, ChEBI:CHEBI:30879, ChEBI:CHEBI:35924, ChEBI:CHEBI:50058; |
DNA Binding | |
EC Number | 1.11.1.- |
Enzyme Function | FUNCTION: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. {ECO:0000250|UniProtKB:P38013}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (1); Chain (1); Disulfide bond (2); Domain (1) |
Keywords | Antioxidant;Disulfide bond;Oxidoreductase;Peroxidase;Redox-active center |
Interact With | |
Induction | |
Subcellular Location | |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 17,408 |
Kinetics | |
Metal Binding | |
Rhea ID | RHEA:10008 |
Cross Reference Brenda |