Detail Information for IndEnz0018001307
IED ID IndEnz0018001307
Enzyme Type ID peroxidase001307
Protein Name Catalase-peroxidase 1
CP 1
EC 1.11.1.21
Peroxidase/catalase 1
Gene Name katG1 CJA_2891
Organism Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Cellvibrionales Cellvibrionaceae Cellvibrio Cellvibrio japonicus (Pseudomonas fluorescens subsp. cellulosa) Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa)
Enzyme Sequence MDNNPPTSTGKCPFTHGSVTASGKSNTDWWPNALNLDILHQHDRKTNPLGDDFSYAAAFKTLDLQAVKNDLKALMTDSQDWWPADWGHYGGLFIRMAWHSAGSYRIADGRGGAGTGNQRFAPLNSWPDNGNLDKARRLLWPIKKKYGNKLSWADLMILAGNMAYESMGLKTFGFGGGREDIWHPEKDVYWGSEKEWLAKSGGEGSRYSGERDLENPLAAVMMGLIYVNPEGVDGNPDPLRTAKDIRETFARMAMNDEETVALTAGGHTVGKAHGNGNAANLGPDPEAADVEEQGLGWVNHKTRGIGRDTVTSGIEGAWTTHPTKWDNGYFDMLLNHDWELTKSPAGAWQWKPVSIKEEDMPVDVEDPSIRCTPLMTDADMAMKMDPEYRKISERFYSDPAYFSEVFARAWFKLTHRDLGPKARYLGADVPAEDLIWQDPVPTVDYTLSDADIADLKAKILASGLSVAELVATAWDSARTFRGSDFRGGANGARIRLAPQKDWEGNEPARLQKVLGVFAGIQSGLSKKVSIADLIVVGGAAAVEKAARDAGVNITVPFAPGRGDATDAQTDAESFAPLEPVHDGFRNWVKKDYAVQPEEMLLDRAQLMGLTAPEMTVLVGGMRVLGANYGGSKNGVFTDKVGVLSNDFFVNLTDMAYQWKPTGKNSYNIVERNTGTVKWSATRVDLVFGSNSILRSYAEVYAQDDNREKFVRDFVKAWVKVMNADRFDLK
Enzyme Length 729
Uniprot Accession Number B3PC77
Absorption
Active Site ACT_SITE 99; /note=Proton acceptor; /evidence=ECO:0000255|HAMAP-Rule:MF_01961
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=AH2 + H2O2 = A + 2 H2O; Xref=Rhea:RHEA:30275, ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:17499; EC=1.11.1.21; Evidence={ECO:0000255|HAMAP-Rule:MF_01961}; CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.21; Evidence={ECO:0000255|HAMAP-Rule:MF_01961};
DNA Binding
EC Number 1.11.1.21
Enzyme Function FUNCTION: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. {ECO:0000255|HAMAP-Rule:MF_01961}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Cross-link (2); Metal binding (1); Site (1)
Keywords Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification PTM: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme. {ECO:0000255|HAMAP-Rule:MF_01961}.
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 80,327
Kinetics
Metal Binding METAL 267; /note=Iron (heme b axial ligand); /evidence=ECO:0000255|HAMAP-Rule:MF_01961
Rhea ID RHEA:30275; RHEA:20309
Cross Reference Brenda