| IED ID | IndEnz0018001380 |
| Enzyme Type ID | peroxidase001380 |
| Protein Name |
Hydroxylamine reductase EC 1.7.99.1 Hybrid-cluster protein HCP Prismane protein |
| Gene Name | hcp STM0937 |
| Organism | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) |
| Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Salmonella Salmonella enterica (Salmonella choleraesuis) Salmonella enterica I Salmonella typhimurium Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) |
| Enzyme Sequence | MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDNFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLSVDANAHCDNPMADLQLVSDDLGDLQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECAMEIGQMNFKVMSILDAGETTKYGHPTPTQVNVKATEGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGSYDDRIWTRSIVGWPGVSHLEGDDFGPVIAQAQQMAGFPYSEIPHIITVGFGRQTLLGAADTLIDLVSREKLRHIFLVGGCDGARGERNYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFFTPDLLAILNEKFGLRSVTTVEEDMKQLLSA |
| Enzyme Length | 550 |
| Uniprot Accession Number | Q8ZQE8 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=A + H2O + NH4(+) = AH2 + H(+) + hydroxylamine; Xref=Rhea:RHEA:22052, ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15429, ChEBI:CHEBI:17499, ChEBI:CHEBI:28938; EC=1.7.99.1; Evidence={ECO:0000255|HAMAP-Rule:MF_00069}; |
| DNA Binding | |
| EC Number | 1.7.99.1 |
| Enzyme Function | FUNCTION: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. {ECO:0000255|HAMAP-Rule:MF_00069}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Metal binding (12); Modified residue (1) |
| Keywords | 2Fe-2S;Cytoplasm;Iron;Iron-sulfur;Metal-binding;Oxidoreductase;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00069}. |
| Modified Residue | MOD_RES 405; /note=Cysteine persulfide; /evidence=ECO:0000255|HAMAP-Rule:MF_00069 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 60,088 |
| Kinetics | |
| Metal Binding | METAL 3; /note=Iron-sulfur (2Fe-2S); /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 6; /note=Iron-sulfur (2Fe-2S); /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 18; /note=Iron-sulfur (2Fe-2S); /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 25; /note=Iron-sulfur (2Fe-2S); /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 249; /note=Iron-oxo-sulfur (4Fe-2O-2S); via tele nitrogen; /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 273; /note=Iron-oxo-sulfur (4Fe-2O-2S); /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 317; /note=Iron-oxo-sulfur (4Fe-2O-2S); /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 405; /note=Iron-oxo-sulfur (4Fe-2O-2S); via persulfide group; /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 433; /note=Iron-oxo-sulfur (4Fe-2O-2S); /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 458; /note=Iron-oxo-sulfur (4Fe-2O-2S); /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 492; /note=Iron-oxo-sulfur (4Fe-2O-2S); /evidence=ECO:0000255|HAMAP-Rule:MF_00069; METAL 494; /note=Iron-oxo-sulfur (4Fe-2O-2S); /evidence=ECO:0000255|HAMAP-Rule:MF_00069 |
| Rhea ID | RHEA:22052 |
| Cross Reference Brenda |