Detail Information for IndEnz0018001561
IED ID IndEnz0018001561
Enzyme Type ID peroxidase001561
Protein Name Catalase-peroxidase
CP
EC 1.11.1.21
Peroxidase/catalase
Gene Name katG PC1_2402
Organism Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Pectobacteriaceae Pectobacterium Pectobacterium carotovorum (Erwinia carotovora) Pectobacterium carotovorum subsp. carotovorum (Erwinia carotovora subsp. carotovora) Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Enzyme Sequence MDENKTKPAGKCPVMHGGNTATGSSNTDWWPNALNLDILHQHDTKTNPLGSDFSYRDALKTLDVDALKKDLHALMTDSQEWWPADWGHYGGLMIRMAWHSAGTYRTADGRGGGGTGNQRFAPLNSWPDNVSLDKARRLLWPIKKKYGNKLSWADLIILAGNIAYESMGLKTFGFAFGREDIWHPEKDIYWGSEKEWLAKSTGRYGSDDRTTLENPLAAVQMGLIYVNPEGVDGNPDPLRTAQDMRVTFSRMAMNDEETVALTAGGHTVGKTHGNGDASLLGKAPEGTDVGEQGLGWHNPTGSGKGRYTVTSGLEGAWTTHPTQWDNGFFHMLLNHEWELKKSPAGAWQWEPVFIKEEDKPVDVEDPSIRYNPMMTDADMALKVDPEYRKISERFYQDQAYFSEVFARAWFKLTHRDMGPKTRYLGPDVPQEDLLWQDPVPAGRTDYDVDVVKARIAESSLSISELVATAWDSARTFRGSDMRGGANGARIRLAPQKDWVGNEPERLARVLVVLENIAAATGASVADTIVLAGNVGIEKAAKAAGVNITVPFAPGRGDTTDALTDVESFDVLEPIHDGYRNWLKKDYAVSPEELMLDRTQLMGLTAKEMTVLVGGLRVLGTNYGGTKHGVFTDREGALTNDFFANLTDMKYTWKPYRKDLYEIRDRKTGEVKWTATRLDLVFGSNSILRSYAEVYAQDDNKEKFVNDFVAAWVKVMNADRFDLAE
Enzyme Length 724
Uniprot Accession Number C6DK50
Absorption
Active Site ACT_SITE 99; /note=Proton acceptor; /evidence=ECO:0000255|HAMAP-Rule:MF_01961
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=AH2 + H2O2 = A + 2 H2O; Xref=Rhea:RHEA:30275, ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:17499; EC=1.11.1.21; Evidence={ECO:0000255|HAMAP-Rule:MF_01961}; CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.21; Evidence={ECO:0000255|HAMAP-Rule:MF_01961};
DNA Binding
EC Number 1.11.1.21
Enzyme Function FUNCTION: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. {ECO:0000255|HAMAP-Rule:MF_01961}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Cross-link (2); Metal binding (1); Region (1); Site (1)
Keywords Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification PTM: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme. {ECO:0000255|HAMAP-Rule:MF_01961}.
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 80,669
Kinetics
Metal Binding METAL 266; /note=Iron (heme b axial ligand); /evidence=ECO:0000255|HAMAP-Rule:MF_01961
Rhea ID RHEA:30275; RHEA:20309
Cross Reference Brenda