Detail Information for IndEnz0018001619
IED ID IndEnz0018001619
Enzyme Type ID peroxidase001619
Protein Name Protein URE2
Gene Name URE2 KLLA0D19624g
Organism Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Kluyveromyces Kluyveromyces lactis (Yeast) (Candida sphaerica) Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Enzyme Sequence MQQDMQNGGPGNTISNLSSALRQVNLGNSNTTTDQSNISIDFNQQQLLEEANQGSINAYNAQQQQQEHLQQQAQQQQLHMQQLQQAQQQQAQQQAHQQQQQVHQVQHQHVQQDHMPIGQSQQQAMYQGPNPIDSSRITKFFQNQPMEGYTLFSHRSAPNGFKVAIVLSELNMHYNTIFLDFNLGEHRAPEFVAINPNARVPALIDHNMENLSIWESGAIILHVVNKHYKETGNPLLWSDSLADQAQINAWLFFQTSGHAPMIGQALHFRYFHSQKVKSAVDRYTDEVRRVYGVVEMALAERREALIMDLDSENAAAYSAGTTPLSQSRFFDYPVWLVGDKITVADLSFVPWNNVVDRIGINIKVEFPEVYKWTKHMMRRPAVIKALRGE
Enzyme Length 389
Uniprot Accession Number Q96X43
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Plays an important role in the cellular response to the nitrogen source. URE2 gene plays a major part in the repression of GLN1 and GDH2 genes by glutamine, and is required for the inactivation of glutamine synthetase. URE2 gene product may catalytically inactivate GLN3 in response to an increase in the intracellular concentration of glutamine (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Domain (2)
Keywords Nitrate assimilation;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 44,395
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda