IED ID |
IndEnz0018001619 |
Enzyme Type ID |
peroxidase001619 |
Protein Name |
Protein URE2
|
Gene Name |
URE2 KLLA0D19624g |
Organism |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Saccharomycotina (true yeasts)
Saccharomycetes
Saccharomycetales
Saccharomycetaceae
Kluyveromyces
Kluyveromyces lactis (Yeast) (Candida sphaerica)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
|
Enzyme Sequence |
MQQDMQNGGPGNTISNLSSALRQVNLGNSNTTTDQSNISIDFNQQQLLEEANQGSINAYNAQQQQQEHLQQQAQQQQLHMQQLQQAQQQQAQQQAHQQQQQVHQVQHQHVQQDHMPIGQSQQQAMYQGPNPIDSSRITKFFQNQPMEGYTLFSHRSAPNGFKVAIVLSELNMHYNTIFLDFNLGEHRAPEFVAINPNARVPALIDHNMENLSIWESGAIILHVVNKHYKETGNPLLWSDSLADQAQINAWLFFQTSGHAPMIGQALHFRYFHSQKVKSAVDRYTDEVRRVYGVVEMALAERREALIMDLDSENAAAYSAGTTPLSQSRFFDYPVWLVGDKITVADLSFVPWNNVVDRIGINIKVEFPEVYKWTKHMMRRPAVIKALRGE |
Enzyme Length |
389 |
Uniprot Accession Number |
Q96X43 |
Absorption |
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Active Site |
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Activity Regulation |
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Binding Site |
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Calcium Binding |
|
catalytic Activity |
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DNA Binding |
|
EC Number |
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Enzyme Function |
FUNCTION: Plays an important role in the cellular response to the nitrogen source. URE2 gene plays a major part in the repression of GLN1 and GDH2 genes by glutamine, and is required for the inactivation of glutamine synthetase. URE2 gene product may catalytically inactivate GLN3 in response to an increase in the intracellular concentration of glutamine (By similarity). {ECO:0000250}. |
Temperature Dependency |
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PH Dependency |
|
Pathway |
|
nucleotide Binding |
|
Features |
Chain (1); Domain (2) |
Keywords |
Nitrate assimilation;Reference proteome |
Interact With |
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Induction |
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Subcellular Location |
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Modified Residue |
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Post Translational Modification |
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Signal Peptide |
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Structure 3D |
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Cross Reference PDB |
- |
Mapped Pubmed ID |
- |
Motif |
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Gene Encoded By |
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Mass |
44,395 |
Kinetics |
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Metal Binding |
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Rhea ID |
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Cross Reference Brenda |
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