| IED ID | IndEnz0020000019 |
| Enzyme Type ID | mannase000019 |
| Protein Name |
Probable beta-mannosidase EC 3.2.1.25 Mannanase Mannase |
| Gene Name | C33G3.4 |
| Organism | Caenorhabditis elegans |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
| Enzyme Sequence | MRTSLVVCLFWLLFQLHTTHGYNTLVNLAGNWEFSSSNKTVNGTGTVPGDIYSDLYASGIIDNPLFGENHLNLKWIAEDDWTYSRKFRLIDLDDTVGAFLEIESVDTIATVYVNGQKVLHSRNQFLPYHVNVTDIIALGENDITIKFKSSVKYAEKRADEYKKIFGHSLPPDCNPDIYHGECHQNFIRKAQYSFAWDWGPSFPTVGIPSTITINIYRGQYFHDFNWKTRFAHGKWKVAFEFDTFHYGARTIEYSVQIPELGIKESDYYRLSATKSLQTRSKNIMSLSIPMEHEPERWWPNGMGEQKLYDVVVSMGGQVKEKKIGFKTVELVQDLIDPKKPEKGRNFYFKINDEPVFLKGTNWIPVSMFRSDRENIAKTEFLLDSVAEVGMNAIRVWGGGFYESNHFYYYASKKGILVWQDLMFACALYPTTEEFIQNAEEEVSYNVDRISQHTSVIVFSGNNENEAAIRGHWWKASNYTESQQVKDYVLLYQRLAKIAKKVAPTIPFIMSSPSNGVETEEEGGVSKNPYDVRYGDIHYYNEFVNLWRDDTYLTPRCASEYGVQSYPMKETMLNWINESDWEYTSKAMFHRQHHPGGIATNLLMIFQHLPIPAECGSKSVSDVPSCKYISSASYMSRLAYFSQVHQSIALKTQTLHYRRFRNTTTNEGLGNTMCAMYWQLNDVWAAPTWSTIDFEQNWKMAHYEARRFFSNVAVYSFADETDFNLKVFLLNDNPYLLHNITVNVQMLSWGNGLDPILTNEFHIDSVPAGSSEVLKTGITFSKITELSEYLYVSTLYDSSGVKIHEDVLVPDFLFEVDFNTFGDVQISDVQRIDEKTYDLTITTDRVSPFTWITCKKPFTGWFSDNGFHMIQRLRKIRLIAKFEVDLEKSDFTVCNLKNCYV |
| Enzyme Length | 900 |
| Uniprot Accession Number | Q93324 |
| Absorption | |
| Active Site | ACT_SITE 463; /note=Proton donor; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.; EC=3.2.1.25; |
| DNA Binding | |
| EC Number | 3.2.1.25 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Glycosylation (7); Signal peptide (1) |
| Keywords | Glycoprotein;Glycosidase;Hydrolase;Lysosome;Reference proteome;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Lysosome {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..21; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 12097347; 17164286; 19343510; 21177967; 22286215; 22347378; 22560298; 23800452; 25487147; |
| Motif | |
| Gene Encoded By | |
| Mass | 103,978 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |