Detailed Information for N00008
IPAD-DB ID N00008
Name AGuIX@PEG@LPFFD@Cy5.5
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ1-42
Effects Bind selectively amyloid plaque constituted by Aβ protein on ex vivo AD mouse hippoacampus; bind and to discriminate Aβ1–42 amyloid fibrils
Research Models APPswe/PS1A246E/TTR mice; docking study
Main Source
Ref. Link