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Detailed Information for N00009
IPAD-DB ID
N00009
Name
ANNP/siRNA
Category
Nano-inhibitors
EC
50
IC
50
Inhibition
Toxicity
low cytotoxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
PASS
Target Protein
β-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Effects
Down-regulate BACE1 gene expression in PC12 cells
Research Models
BEnd.3 and PC12 cells
Main Source
Ref. Link