Detailed Information for N00009
IPAD-DB ID N00009
Name ANNP/siRNA
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity low cytotoxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein β-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Effects Down-regulate BACE1 gene expression in PC12 cells
Research Models BEnd.3 and PC12 cells
Main Source
Ref. Link