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Detailed Information for N00011
IPAD-DB ID
N00011
Name
anti-Aβ1-42-NPs
Category
Nano-inhibitors
EC
50
IC
50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
PASS
Target Protein
Aβ1-42
Effects
Complete correction of the memory defect; significant reduction of the Aβ soluble peptide and its oligomer level in the brain; significant increase of the Aβ levels in plasma
Research Models
NIHS and Tg2576 mice
Main Source
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