Detailed Information for N00011
IPAD-DB ID N00011
Name anti-Aβ1-42-NPs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Aβ1-42
Effects Complete correction of the memory defect; significant reduction of the Aβ soluble peptide and its oligomer level in the brain; significant increase of the Aβ levels in plasma
Research Models NIHS and Tg2576 mice
Main Source
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