Detailed Information for N00026
IPAD-DB ID N00026
Name curc-PLGA-nps
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ
Effects Enhance cell proliferation in the hippocampus and SVZ of adult rats; activate neuroregulatory Wnt/β-catenin signaling pathway; reverse Aβ-mediated inhibitory effects on hippocampal neurogenesis and learning and memory in an AD rat model
Research Models Kinetic study; Wistar rats
Main Source
Ref. Link