Detailed Information for N00035
IPAD-DB ID N00035
Name Fe3O4@PDA-coated hUC-MSCs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity low toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ
Effects Improve cognitive function in APP/PS1 transgenic mice that ingcreasing Aβ deposition, BDNF and Syn expression level; regulation of hUC-MSCs generates excess neuroprotective factors
Research Models SH-SY5Y cells; APP/PS1 mice
Main Source
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