Detailed Information for N00040
IPAD-DB ID N00040
Name GM1-rHDL
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ1-42
Effects Bind to Aβ1-42 monomer and oligomer with high affinity; accelerate microglia-mediated degradation and brain-to-blood efflux of Aβ1-42
Research Models Primary microglial cells; SD rats and ICR mice
Main Source
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