Detailed Information for N00044
IPAD-DB ID N00044
Name HPG-trehalose
Category Nano-inhibitors
EC50 -
IC50 -
Inhibition -
Toxicity
ROS(reactive oxygen species) Functional HPG interacts with LO either at extra-/intracellular space and inhibits ROS generation.
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ
Effects (1) HPG-trehalose transforms the fibrils into amorphous aggregates or smaller fragments; (2) inhibit intracellular protein aggregation;
Research Models HT22 neuronal cells and HD150Q neuronal cells
Main Source
Ref. Link