Detailed Information for N00047
IPAD-DB ID N00047
Name Single-walled carbon nanotubes (SWCNTs)  
Category Nano-inhibitors
EC50 -
IC50 -
Inhibition -
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ1-42
Effects (1) SWCNTs could partially destroy the preformed Aβ fibrils and form the Aβ-surrounded–SWCNTs conjugates, as well as reduce the β-sheet structures; (2) SWCNTs Dissociate the Preformed Aβ1−42 Fibrils and Form Large Aβ1−42 Surrounded SWCNTs Conjugates;
Research Models Molecular dynamics (MD) simulations and SH-SY5Y
Main Source
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