Detailed Information for N00053
IPAD-DB ID N00053
Name TFB-SLNs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Aβ
Effects Overall pharmacokinetic behavior of TFB was improved through nanoparticles than solution/suspension and i.n. route was proved to be advantageous over i.v. and oral route of administration
Research Models SD rats; in vitro
Main Source
Ref. Link