Detailed Information for N00059
IPAD-DB ID N00059
Name W20/XD4-SPIONs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity low cytotoxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Aβ
Effects Specifically recognize AβOs in AD Brains; promote microglial phagocytosis of AβOs
Research Models Nude, C57 and APP/PS1 mice; BV-2 and SH-SY5Y cells
Main Source
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