Detailed Information for N00062
IPAD-DB ID N00062
Name αNAP-GM1-rHDL
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity protect neurons from Aβ1-42 oligomer-induced toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ1-42
Effects Reduce Aβ deposition, ameliorates neurologic damage, and rescue memory deficits in AD model mice
Research Models Primary microglial cells; SD rats and ICR mice
Main Source
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