Detailed Information for N00072
IPAD-DB ID N00072
Name ApoE3
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Acetylcholinesterase (AChE)
Effects ApoE3-coated polymeric nanoparticles have improved pharmacokinetic profile and exhibited significant increase in the brain levels of DNP, which concludes the improvement in the brain uptake of DNP
Research Models HepG2 and U87 cells；in vitro
Main Source
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