Detailed Information for N00073
IPAD-DB ID N00073
Name donepezil-loaded PLGA nanoparticles
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Acetylcholinesterase (AChE)
Effects Amplify the physiological action of acetylcholine (ACh) in AD patients
Research Models SD rats
Main Source
Ref. Link