Detailed Information for N00079
IPAD-DB ID N00079
Name AC-HAp-NPs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Butyrylcholinesterase (BChE)
Effects Inhibitors increase acetylcholine levels by inhibiting AChE and BChE of the cholinergic synapse, improving function and alleviating symptoms of neurological disorders such as A
Research Models This study sought to identify phytoconstituents that might bind to the crucial AD amyloid hypothesis targets while also testing the ability of the synthesized AC-HAp NPs to inhibit AChE
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