Detailed Information for N00092
IPAD-DB ID N00092
Name Ga-terminated dendrimers
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Aβ
Effects Inhibit the primary and secondary nucleation of Aβ fibrillization and disrupt the Aβ preformed fibrils
Research Models SH-SY5Y cells；MD
Main Source
Ref. Link