Detailed Information for N00101
IPAD-DB ID N00101
Name Au@PL
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ
Effects (1) In the presence of Au@PL, the total fibril amount was drastically decreased.(2) the aggregation prone site of Aβ is blocked by interior layer of Au@PL(3) the insertion of Aβ in PL makes distance among Au@PL even closer than untreated Au@PL results in the highest EF values among all samples
Research Models This study is to observe Aβ by Raman spectroscopy.
Main Source
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