mesoporous nano-selenium (MSe) release delivery system (MSe-Res/Fc-β-CD/Bor)
Category
Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
PASS
Target Protein
Aβ
Effects
(1) MSe-Res/Fc-β-CD/Bor inhibited aggregation of β-amyloid proteins (Aβ) , mitigated oxidative stress, and suppressed tau hyperphosphorylation, while protecting nerve cells and successfully improving memory impairment in APP/PS1 mice.(2) MSe-Res/Fc-β-CD/Bor could be a prospective drug for treating AD.
