Detailed Information for N00125
IPAD-DB ID N00125
Name hydroxylated single-walled carbon nanotubes (SWCNTs)  
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ
Effects (1) Nonpolar interactions, and especially van der Waals forces, contributed most of the free energy of binding in the SWNT-OH-Aβ complex. (2) Two regions of the Aβ pentamer were identified to interact with SWNT-OH, spanning H13-Q15 and V36-G38.
Research Models Molecular dynamics simulations
Main Source
Ref. Link