Detailed Information for N00138
IPAD-DB ID N00138
Name dendrimer–SA complexes
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity The sialic acid conjugated dendrimeric polymers were able to attenuate Aβ toxicity at micromolar concentrations, or approximately three orders of magnitude lower concentrations than the soluble sialic acid.
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ1-40
Effects The sialic acid conjugated dendrimeric polymers were able to attenuate Aβ toxicity at micromolar concentrations, or approximately three orders of magnitude lower concentrations than the soluble sialic acid.
Research Models Human neuroblastoma SH-SY5Y cells
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