Detailed Information for N00146
IPAD-DB ID N00146
Name Cationic phosphorus dendrimers (CPDs)
Category Nano-inhibitors
EC50
IC50 1μM
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ1-28
Effects (1) CPDs modify the aggregation of both amyloid peptide Aβ 1–28 and MAP-Tau protein;(2) CPDs reduce toxicity caused by aggregated forms of Aβ 1–28.
Research Models Mouse neuroblastoma (N2a) cell
Main Source
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