Detailed Information for N00148
IPAD-DB ID N00148
Name resveratrol-loaded lipid-core nanocapsule(RSV-LNC)
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ1-42
Effects (1) It is important to note that the treatment with RSV-LNC, at the same dosage, significantly attenuated this impairment triggered by Aβ1-42 (p < 0.001) (2) indicating that only rats treated with RSV-LNC were able to distinguish between familiar and new objects following Aβ infusion (3) Treatment with vehicle (EtOH 50 % or LNC, respectively) had no effects on the spontaneous alternation and recognition memory impairments triggered by Aβ
Research Models Male adult Wistar rats
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