Detailed Information for N00149
IPAD-DB ID N00149
Name chrysin loaded lipid-core nanocapsules (LNCs)
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Aβ1-42
Effects (1) C1-LNC and C5-LNC displayed significant effect against Aβ₁−₄2, via attenuation of oxidative stress and neuroinflammation, modulation of neurochemical and behavioral changes in a model of AD. (2) LNCs (mainly C5-LNC) can be a promising biomedical tool and a new therapeutic approach for treatment and prevention of AD.
Research Models Aged female mice
Main Source
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