Detailed Information for N00161
IPAD-DB ID N00161
Name BQCA-SA-P80-NPs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ1-42
Effects (1) BQCA-SA-P80-NPs significantly improve the therapeutic efficacy of AChE inhibitor, donepezil (DPZ) , indicating its potentiating effects(2) suggesting an improved brain bioavailability and reduced peripheral side effects of BQCA
Research Models SH-SY5Y cells
Main Source
Ref. Link