Detailed Information for N00165
IPAD-DB ID N00165
Name Curcumin-Loaded Nanocapsules Reverses(NCLL)
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ25-35
Effects (1) The antidepressant-like effect of curcumin-loadednanocapsules (NLC C) against the Ab25-35-induced neurotoxicity in mice (2) NLC C were able to restore the Ab25-35-generated oxidative stress in the prefrontal cortex(3) ,NLC C displayed superior effects than the free curcumin.
Research Models Swiss male mice(40g-50g)
Main Source
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